According to computational model, pillars having a cathodic return electrode above the INL and active anodic ring electrode at the surface of the implant would enable lower stimulation threshold, compared to planar arrays with circumferential return, but suffer from greater cross-talk between the neighboring pixels. Significance. 3D electrodes in subretinal prostheses help reduce electrode-tissue separation and decrease stimulation thresholds to enable smaller pixels, and thereby improve visual acuity of prosthetic vision.Thomas Flores, Xin Lei, Tiffany Huang, Henri Lorach, Roopa Dalal, Ludwig Galambos, Theodore Kamins, Keith Mathieson and Daniel PalankerPublished 5 March 2018 • © 2018 IOP Publishing Ltd Journal of Neural Engineering, Volume 15, Number 3

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